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Lab Members v2 - Nikki Thadani - Postdoctoral Fellow https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568919013549-DX07ROGIP6M8NYUZXDWL/image-asset.jpeg Lab Members v2 - Jonathan Frazer - Postdoctoral Fellow https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1563289603897-HR6D2W1AKE16D853GF51/Mafalda_Figueiredo_Dias.jpg Lab Members v2 - Mafalda Figueiredo Dias - Postdoctoral Fellow https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1563289382597-YIFV08TR6P9X4WY8VIW2/david_ding.jpg Lab Members v2 - David Ding - Graduate Student https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568919223437-4RYEDUEN7TOKEMCZ4YK6/Nathan_Rollins.jpg Lab Members v2 - Nathan Rollins - Graduate Student https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1563289546090-09EB5XT7UZCCGM7XA6TW/image-asset.jpeg Lab Members v2 - June Shin - Graduate Student 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https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568918917137-PKZYQA82K92RKE49E4YT/Nicole_Thadani.jpg Nikki Thadani https://www.deboramarkslab.com/aaron-kollasch daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568917654740-J5GEYSU5I7EOJUJFXHCO/Aaron.jpg Aaron Kollasch https://www.deboramarkslab.com/amy-tam daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1563472416628-GRGEGHGP9E01LSDAAB4I/Amy_tam.JPG Amy Tam https://www.deboramarkslab.com/berk-alpay daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1589842907588-19G2TI3F0ZWK5B2JPNS9/Berk_Alpay.jpg Berk Alpay https://www.deboramarkslab.com/mafalda-figueiredo-dias daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562091303212-8GGROKBJ0ZC8K4IYFXO5/Mafalda_Figueiredo_Dias.jpg Mafalda Figueiredo Dias https://www.deboramarkslab.com/rose-orenbuch daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568919298064-5Y4EEKWLPG89FBFM5KAU/Rose_Orenbuch.jpg Rose Orenbuch https://www.deboramarkslab.com/kasia-kready daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1575569839280-T7IOGDSAWS85XT6F2IRQ/Kasia_Kready.jpg Kasia Kready https://www.deboramarkslab.com/david-ding daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562092567774-IIGT0QJJOQJ1EU0GBK0E/david_ding.jpg David Ding https://www.deboramarkslab.com/nathan-rollins daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568919223437-4RYEDUEN7TOKEMCZ4YK6/Nathan_Rollins.jpg Nathan Rollins https://www.deboramarkslab.com/ada-shaw daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562097130918-XWYIKLOX468H3MRJQP88/Ada_Shaw.jpg Ada Shaw https://www.deboramarkslab.com/siranush-babakhanova daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568919387882-L9Z7TWCBQWG363SKSCE0/Siranush_Babakhanova.png Siranush Babakhanova https://www.deboramarkslab.com/tessa-green daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568918952572-FC97XNBY6BWVXIJGHXYS/tessa_green.jpg Tessa Green https://www.deboramarkslab.com/alan-amin daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1568920316764-E1UMHRE2EB5PDR0LJPM8/Amin_Alan.jpg Alan Amin https://www.deboramarkslab.com/mrunali-manjrekar daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1589842926695-UQJDL4DE0ZADOIGAV251/Mrunali_Manjrekar.jpg Mrunali Manjrekar https://www.deboramarkslab.com/aashna-shah daily 0.75 2020-08-11 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1582058861558-APUJXD5FDRCAWVC75KV9/Aashna_Shah.png Aashna Shah https://www.deboramarkslab.com/debora-marks daily 0.75 2020-08-19 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1597090759514-JWHUY07H522P5DQ28XNM/E7DE9340-2268-4E06-8579-BE71FF82E501-957-000000C587719434+%281%29.jpg Debora Marks https://www.deboramarkslab.com/home-page-20 daily 0.75 2021-02-09 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1617056132899-M6STR1J5Q4HBB6VZN4AD/Marks_Lab_frontpage_graphic.png Home Page 2.0 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1597089316755-YIL9RWFFH08E5RCQ12AL/MarksLabHomepage_proto3_gradient.png Home Page 2.0 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1587402010177-P2JFJYUBNJBZTKFKUDPV/couplings.png Home Page 2.0 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1563305497352-UCUXI4S4AGXTRTTKZQMX/image-asset.jpeg Home Page 2.0 https://www.deboramarkslab.com/home-page-20-slider daily 0.75 2021-02-10 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1597089316755-YIL9RWFFH08E5RCQ12AL/MarksLabHomepage_proto3_gradient.png Home Page 2.0 (slider) - WHAT WILL WE DO WHEN THERE ARE A BILLION GENOMES? We develop computational approaches to make sense of genetic variation. And we learn to design biological tools for environmental and human health. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1612993952709-WF1WHWGIEXYL4QMGZZ7D/F1.large.jpg Home Page 2.0 (slider) - Generative probabilistic biological sequence models that account for mutational variability Here we introduce a structured emission distribution (the MuE distribution) that accounts for mutational variability (substitutions and indels) and use it to construct generative and predictive hierarchical Bayesian models (H-MuE models). https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1612990813981-U7LOCVMULFSJ7LLBVZ82/couplings.jpg Home Page 2.0 (slider) - EVOLUTIONARY COUPLINGS PREDICTING PROTEIN STRUCTURES, COMPLEXES, AND CONFORMATIONAL PLASTICITY FROM EVOLUTION https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1612993196114-6JRZX9AIKPEWUWCV80UL/Screenshot+2021-02-10+163944.png Home Page 2.0 (slider) - Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact Here, we used multiplexed, sequencing-based assays to measure the effects of 2,695 VKOR missense variants on abundance and 697 variants on activity in cultured human cells. https://www.deboramarkslab.com/about-us-1 daily 0.75 2021-03-29 https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562704190491-P147SES1N13DFBXBOQ1W/disorderPaper_cropped.png About Us (Copy) - Structured States of Disordered Proteins from Genomic Sequences (Copy) (Copy) https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562700413912-ILPKLU06CZ034JMIDFXO/Deep_generative_models.png About Us (Copy) - Deep generative models of genetic variation capture the effects of mutations (Copy) (Copy) https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562704356907-85ZEOJ6KCY4JFF2G361W/3D_RNA_and_functional_interactions_from_evolutionary_couplings.jpg About Us (Copy) - 3D RNA and Functional Interactions from Evolutionary Couplings (Copy) (Copy) https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562700840862-0ASKWO1FKLNXWHDWQ86F/Model_constraints_on_sequences.jpg About Us (Copy) - Mutation effects predicted from sequence co-variation (Copy) (Copy) https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1567521948824-1O9S4FQHIAJKQHJNJ0TH/Inferring_protein_3D_structure_from_deep_mutation_scans.png About Us (Copy) - Inferring protein 3D structure from deep mutation scans (Copy) (Copy) https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/1562701790175-6C06N5WTBONL2Q54O8LU/Population-specific_design_of_de-immunized_protein_biotherapeutics.PNG About Us (Copy) - 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Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/3396bf45-e02a-4fa8-905e-fa875bd4ac99/IMG_7830.jpeg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/96fd262d-5c3d-4d2f-b1cb-417435dcdc58/Sarah+%26+Sarrah.png Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/c7d224a6-6009-4740-a001-a0dd3c771665/9719643c-8e5b-4f0d-aee3-11a7d072d1f6.jpg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/10908a3f-f303-4592-9257-b9c3d0485f3b/IMG_8433.jpg Shenanigans - Make it stand out NeurIps 2024 reunion! https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/0c3b0abb-ad9a-40fb-8799-643b4719f002/Image+from+iOS+%283%29.jpg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/bd98ccb8-bf99-4df3-b81f-2b871bef60c5/B4B2E813-0946-406F-AF9C-38B3B14755C2_1_105_c.jpeg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/68efbb25-4718-4c12-859a-ee1cdc51fe4f/Marks+Lab+Feb+2024.png Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/32557a77-4139-48e1-8646-2cd88f444ad2/IMG_7456.jpg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/2819cf55-9fc0-4ead-bff1-79d370765ddc/DSC_5387.jpg Shenanigans https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/4fa19015-2cc6-428b-af53-1945b14abdca/20220429_221112%7E2.jpg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/0c3d79d5-de27-4d8e-8886-b33b880e8752/Screen+Shot+2024-03-06+at+9.46.44+AM.png Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/88b20033-053b-4851-bffd-ab4684d4615d/IMG_9151.jpeg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/e5875acc-975b-4d14-82cc-95c24497b2c3/Steffanie+05.jpg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/b84ae151-46c4-4176-a568-cac87fbf6cb7/IMG_7818.jpeg Shenanigans - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/61363d12-fec1-4cc3-aed4-5a3c97623466/Image+from+iOS+%284%29.jpg Shenanigans https://images.squarespace-cdn.com/content/v1/5d14ec146b07c40001a84bef/df872b99-a926-475c-ad12-963b7c0bac03/D6DEF2FF-21FA-44A3-9F2D-202386C8FCBD_1_105_c.jpeg Shenanigans - 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